Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
About
The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV.
The Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) grant program invites researchers and organizations to conduct innovative analyses of existing datasets to advance understanding of substance use disorders, prevention strategies, and health service delivery. This program is designed for researchers who can leverage public use datasets, community-based data, or clinical datasets to study the etiology, epidemiology, and trajectories of drug using behaviors—including alcohol, tobacco, prescription drugs, and other substances. The grant supports investigations into prevention of drug use and HIV, risk and resilience factors in psychopathology development, and strategies for implementing effective prevention and treatment services. This opportunity is ideal for academic institutions, federal agencies, faith-based organizations, community-based organizations, and historically underrepresented institutions including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, and tribal governments. By utilizing existing data rather than conducting new clinical trials, researchers can accelerate the pace of discovery while maximizing the value of previously collected information. This approach allows for cost-effective research that addresses critical gaps in substance use epidemiology and health outcomes, ultimately contributing to improved prevention and treatment strategies across diverse populations.
Funding Facts
● Applications openDeadline
December 3, 2027
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Funding Range
Varies by cycle
Deadline
2027-12-03
Grant Type
federal
Application Cycle
Annual
Best For
Academic research institutions, HBCUs, Hispanic-serving institutions, tribal governments, community-based organizations, and researchers conducting secondary data analysis in substance use epidemiology and prevention
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Govern
Frequently Asked Questions
Who is eligible for Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)?
Eligible applicants include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), eligible federal agencies, faith-based and community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Indian/Native American Tribal Governments. For complete and current eligibility requirements, visit the official NIH website or the specific Notice of Funding Opportunity announcement.
How much funding does Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) provide?
Specific funding amounts are not listed in the current information available. Award amounts typically vary by cycle and project scope. Contact the National Institute on Drug Abuse (NIDA) or visit the official NIH grants website for current funding levels and budgetary guidelines for this funding opportunity.
How do I apply for Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)?
Applications are submitted through the NIH grants system, typically via grants.nih.gov. Applicants should prepare a detailed research proposal outlining their analysis of existing datasets, the research questions to be addressed, and the expected impact on substance use research and prevention. The application deadline is December 3, 2027. For specific submission instructions, formatting requirements, and technical assistance, consult the official Notice of Funding Opportunity on the NIH website.
What can Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) funding be used for?
Funding supports innovative analyses of existing social science, behavioral, administrative, and neuroimaging datasets to study substance use disorders, prevention strategies, and health service utilization. Allowable uses include research on the etiology and epidemiology of drug-using behaviors (alcohol, tobacco, prescription drugs, and other substances), prevention of drug use and HIV, trajectories of substance use and related consequences, risk and resilience factors in psychopathology, and the development and testing of prevention and treatment service delivery models. Clinical trials are not permitted under this funding mechanism.
Last updated: July 5, 2026