Advancing Global Health
About
The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U. S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.
Advancing Global Health is a Department of State grant program designed to support organizations implementing the America First Global Health Strategy. This nationwide funding opportunity invites eligible applicants to develop and execute projects that save lives, strengthen health systems, enhance operational efficiency, foster self-reliance in partner countries, and ensure U.S. health investments advance American safety, strength, and prosperity. The program operates through an Annual Program Statement (APS) framework with specific Addenda that signal evolving priorities and funding needs. Organizations can submit Statements of Interest addressing bilateral Memoranda of Understanding (MOUs) and identified gaps in global health implementation. With funding ranging from $250,000 to $250,000,000, this represents a significant opportunity for nonprofits, international organizations, research institutions, and implementing partners to advance critical health initiatives globally. Applicants should review the complete APS instructions for detailed eligibility requirements and application procedures. The Department of State collaborates with Embassies and other bureaus to post targeted funding opportunities, making this an excellent avenue for organizations with expertise in global health systems strengthening, disease prevention, health security, and international development.
Funding Facts
● Applications openDeadline
February 14, 2027
Award Amount
$500K - $250M
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Grant Amount
$500K - $250M
Deadline
2027-02-14
Grant Type
federal
Application Cycle
Annual with Addenda-based cycles
Best For
Nonprofits, international organizations, research institutions, and implementing partners focused on global health systems strengthening and bilateral health initiatives
Eligibility
Please see APS instructions for eligibility criteria.
Frequently Asked Questions
Who is eligible for Advancing Global Health?
Eligibility criteria are detailed in the APS instructions provided by the Department of State. Applicants should consult the official APS document for comprehensive requirements. Generally, eligible entities may include nonprofits, international organizations, research institutions, and implementing partners working on global health initiatives. Visit the Department of State website for the complete APS and current eligibility guidelines.
How much funding does Advancing Global Health provide?
Advancing Global Health awards range from $250,000 to $250,000,000, depending on project scope and funding priorities. Specific funding amounts vary by Addendum and fiscal year. Review the relevant Addendum posted for your area of interest to understand available funding levels.
How do I apply for Advancing Global Health?
Applications are submitted as Statements of Interest (SOIs) following the standard application instructions outlined in the Annual Program Statement. The Department of State posts specific funding opportunities and Addenda that include detailed submission requirements. Applicants must consult the official APS instructions and relevant Addenda on the Department of State website for current deadlines, submission procedures, and required documentation.
What can Advancing Global Health funding be used for?
Funding supports projects that advance the America First Global Health Strategy, including: saving lives, strengthening health systems, enhancing efficiency, fostering self-reliance in partner countries, and complementing bilateral MOUs. Projects may address identified gaps in health implementation. Specific allowable uses are detailed in the relevant Addendum for each funding opportunity.
Last updated: July 5, 2026