Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
About
This Notice of Funding Opportunity (NOFO) encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis. The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research. Proposed Animal and Biological Material Resource Centers must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIP"s NIH-wide mission (https://orip. nih. gov/about-orip). This funding opportunity is designed to support both continuation of existing resources and to develop new ones when appropriate. Of special interest of the announcement is a requirement of the Center"s close coordination with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Applied Research Component should include studies to generate comparative data to increase applicability of NAMs and promote integration of the most predictive human disease models. Prior to pre.
The Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed) grant supports institutions and organizations that maintain specialized research resources serving the biomedical research community. This NIH funding opportunity is designed for organizations operating animal colonies, biological material repositories, and associated research infrastructure that have broad application across multiple NIH Institutes and Centers. The grant funds the development and continuation of resources including laboratory animal colonies, informatics tools, reagents, cell and tissue cultures, organs, and genetic stocks. A key focus area is supporting the integration of new approach methodologies (NAMs) such as cell culture systems, organoids, computational models, and microphysiological systems alongside traditional animal-based research. Research institutions, universities, and established resource centers should apply if they provide research materials and services that enhance scientific rigor, transparency, and reproducibility across the biomedical research landscape. The program emphasizes comparative studies that increase the applicability of alternative methodologies and promote integration of predictive human disease models. This is ideal for established research organizations with infrastructure, expertise, and a track record of serving the broader research community at local, regional, or national levels.
Funding Facts
● Applications openDeadline
September 26, 2028
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Funding Range
Varies by cycle
Deadline
2028-09-26
Grant Type
federal
Application Cycle
Annual (Deadline: September 26, 2028)
Best For
Research institutions, universities, established biological and animal resource centers serving multiple research disciplines
Eligibility
Refer to Section III. Eligibility Information for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Frequently Asked Questions
Who is eligible for Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)?
Domestic U.S. organizations are eligible to apply. Foreign organizations, non-domestic entities, and foreign components of U.S. organizations are not eligible. Applicants must demonstrate that their proposed resource center has broad application to multiple NIH Institutes or Centers and aligns with ORIP's NIH-wide mission. For complete eligibility requirements, refer to Section III of the official Notice of Funding Opportunity or visit the NIH website.
How much funding does Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed) provide?
Funding amounts vary by cycle and are not specified in the current announcement. Contact the NIH Office of Research Infrastructure Programs (ORIP) or check the official NOFO for specific funding levels and budget information for the current application cycle.
How do I apply for Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)?
Applications are submitted through the NIH grants system. Visit grants.nih.gov and locate the specific Notice of Funding Opportunity (NOFO) for this program. Follow all submission guidelines outlined in the official announcement, including required documentation, formatting standards, and institutional certifications. The upcoming deadline is September 26, 2028. Consult the full NOFO for detailed application procedures and requirements.
What can Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed) funding be used for?
Funding supports the establishment and maintenance of animal and biological material resource centers, including: special laboratory animal colonies and associated services; informatics tools and databases; reagents and biological materials; cell, tissue, and organ cultures; and genetic stocks. The program also funds applied research components that generate comparative data on new approach methodologies (NAMs), including cell culture, organoids, computational models, and microphysiological systems. Projects must coordinate with NAM development efforts and promote integration of predictive human disease models.
Last updated: July 5, 2026