Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)
About
This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enable collaborative research and benefit broad research communities at large. The NOFO supports two existing construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program. The BRF program supports the construction or modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research in all areas. Intended facilities include shared research spaces, core facilities, biorepositories, or other shared-use resource facilities that serve a broad scientific community with a significant, long-term impact on biomedical research. The HRF program funds the development of HIV/AIDS research or research-supporting resources that the empowered research activities must align with the NIH Office of AIDS Research (OAR) priorities, as outlined at OAR HIV/AIDS Research Priorities, including research focusing on the long-term health consequences of HIV infection. NIH encourages applications from institutions across all geographic regions of the country, including Institutions of Emerging Excellence (IEE) in biomedical research, to strengthen the nation"s research capacity.
The Development of Collaborative Research Facilities or Research-Resource Facilities (C06) grant is designed for institutions seeking to build or modernize shared-use research facilities that advance biomedical research across the nation. This NIH-sponsored program supports two primary tracks: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program. The BRF program funds construction and modernization of facilities supporting basic, translational, clinical, and behavioral science research, including shared research spaces, core facilities, biorepositories, and other collaborative research resources. The HRF program specifically supports HIV/AIDS research infrastructure aligned with NIH Office of AIDS Research priorities, including facilities addressing long-term health consequences of HIV infection. With funding ranging from $2,000,000 to $8,000,000, this grant is ideal for research institutions across all geographic regions, including Institutions of Emerging Excellence, looking to strengthen research capacity and create collaborative environments that serve broad scientific communities. Researchers and institutional leaders should apply if they aim to develop facilities with significant, long-term impact on their research communities.
Funding Facts
● Applications openDeadline
January 25, 2028
Award Amount
$2M - $8M
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Grant Amount
$2M - $8M
Deadline
2028-01-25
Grant Type
federal
Application Cycle
Annual
Best For
Research institutions seeking to develop or modernize shared-use research facilities, including those focused on biomedical research or HIV/AIDS research
Eligibility
See Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Frequently Asked Questions
Who is eligible for Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)?
U.S.-based research institutions are eligible, including those in all geographic regions and Institutions of Emerging Excellence in biomedical research. Foreign organizations and non-domestic components of U.S. organizations are not eligible. For complete eligibility requirements, including specific institutional requirements, consult Section III of the Notice of Funding Opportunity on the official NIH website.
How much funding does Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed) provide?
This grant provides funding between $2,000,000 and $8,000,000 per award. The specific amount available may vary by funding cycle and application scope. Check the official NOFO for current funding details.
How do I apply for Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)?
Applications are submitted through the NIH electronic submission system (eRA Commons). Applicants should review the complete Notice of Funding Opportunity for detailed submission instructions, required documentation, and formatting guidelines. Visit the NIH website to access the official NOFO and submission portal.
What can Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed) funding be used for?
Funding supports construction or modernization of biomedical research facilities, including shared research spaces, core facilities, biorepositories, and research-supporting resource facilities. For the BRF program, facilities must advance basic, translational, clinical, or behavioral science research. For the HRF program, facilities must support HIV/AIDS research aligned with NIH Office of AIDS Research priorities. Clinical trial facilities are not supported under this mechanism.
Last updated: July 5, 2026