Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed)
About
The purpose of this notice of funding opportunity (NOFO) is to establish a Center that trains researchers in formal product development for new substance use disorder (SUD) pharmacotherapeutics and to advance the best concepts through initial experiments via technical and financial support.
The Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed) grant is designed for research institutions and organizations committed to advancing treatment options for substance use disorders. This funding opportunity supports the creation of a specialized center that combines researcher training with practical product development for new SUD pharmacotherapeutics. The grant funds formal education in product development processes alongside technical and financial support to advance promising concepts through initial experimental phases. Researchers and institutions focused on drug development, addiction medicine, and behavioral health should consider applying. This program is particularly valuable for organizations seeking to bridge the gap between basic research and translational science in the substance use disorder treatment space. The grant explicitly prohibits clinical trials, focusing instead on preclinical work and researcher capacity building. Both domestic and international organizations are eligible, making this a global opportunity to strengthen the SUD pharmacotherapeutics research pipeline. Applicants should review the complete Notice of Funding Opportunity (NOFO) for detailed eligibility requirements and submission guidelines.
Funding Facts
● Applications openDeadline
September 30, 2026
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Funding Range
Varies by funding cycle
Deadline
2026-09-30
Grant Type
federal
Application Cycle
Annual
Best For
Research institutions, academic medical centers, and organizations developing substance use disorder pharmacotherapeutics
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Frequently Asked Questions
Who is eligible for Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed)?
Eligible applicants include both domestic and international organizations. Non-U.S. entities and non-domestic components of U.S. organizations may apply. Foreign components as defined in the NIH Grants Policy Statement are allowed. For complete eligibility criteria, refer to Section III. Eligibility Information in the official Notice of Funding Opportunity (NOFO).
How much funding does Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed) provide?
Specific funding amounts vary by funding cycle. Consult the official NOFO and the funding agency's website for current budget information and allowable funding ranges for this grant cycle.
How do I apply for Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed)?
Applications are submitted through the official grant portal specified in the Notice of Funding Opportunity. Applicants should carefully review all submission requirements, formatting guidelines, and required documentation outlined in the NOFO. Visit the funding agency's official website for the complete application instructions, deadlines, and submission procedures.
What can Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed) funding be used for?
Funding supports establishing a center that provides formal training for researchers in product development for new SUD pharmacotherapeutics and offers technical and financial support to advance promising concepts through preclinical experiments. Clinical trials are not permitted under this grant. Funds may support center infrastructure, researcher training programs, and preclinical research activities.
Last updated: July 5, 2026