Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed)
About
Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed) is a federal funding opportunity from National Institutes of Health. This forecasted grant opportunity (FOR-CA-25-087) is available nationwide for eligible applicants.
The Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed) is a federal funding opportunity designed to support early career scientists and small business innovators in advancing their research and commercialization efforts. Offered through the National Institutes of Health, this Small Business Transition Grant (STTR) program helps bridge the gap between basic research and commercial application, enabling entrepreneurs to develop and test innovative scientific solutions. The R41/R42 mechanism provides two-phase funding to support feasibility studies and subsequent development work, excluding clinical trial research. This grant is ideal for small business owners with scientific expertise who are ready to translate their research discoveries into viable commercial products or services. Early career scientists looking to launch or expand their biotech, medical device, pharmaceutical, or life sciences ventures will find this opportunity particularly valuable for de-risking their technology and attracting future investment. The program emphasizes innovation, scientific merit, and commercialization potential, making it a cornerstone funding source for entrepreneurial researchers nationwide.
Grant Details
Funding Range
Varies by phase (Phase I and Phase II)
Grant Type
Federal (NIH SBIR/STTR Program)
Application Cycle
Based on published Notice of Funding Opportunity (FOR-CA-25-087) — check grants.nih.gov for timing and deadline details
Best For
Early career scientists, small businesses, startup companies developing innovative biotech, medical device, pharmaceutical, and life sciences technologies
Frequently Asked Questions
Who is eligible for Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed)?
This grant is designed for early career scientists and small businesses engaged in research and development. Specific eligibility criteria, including firm size requirements, research focus areas, and applicant qualifications, will be detailed in the Notice of Funding Opportunity when published. Visit the NIH SBIR/STTR program website or grants.nih.gov for complete eligibility requirements and the official Funding Opportunity Announcement (FOR-CA-25-087).
How much funding does Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed) provide?
The funding amount varies by phase and project scope. Phase I (R41) and Phase II (R42) awards typically support different project stages with corresponding budget levels. For specific funding amounts and budget guidelines applicable to your project, consult the official NIH Notice of Funding Opportunity or contact the relevant NIH institute or center administering the award.
How do I apply for Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed)?
Applications are submitted through Grants.gov using the NIH SBIR/STTR application forms and guidelines. When the Notice of Funding Opportunity is published (identified as FOR-CA-25-087), complete details on application procedures, deadlines, and required documentation will be available. Review the official FOA on grants.nih.gov and prepare your proposal addressing scientific innovation, commercial potential, and feasibility of your research concept.
What can Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed) funding be used for?
Funding supports research, development, and commercialization activities for innovative scientific projects. Permissible uses typically include personnel costs, equipment, supplies, and other direct research expenses. However, clinical trial research is explicitly excluded. Detailed allowable costs and restrictions will be specified in the official Notice of Funding Opportunity. Review NIH cost principles and the specific FOA for comprehensive guidance on eligible expenditures.
Last updated: March 1, 2026