GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
About
The Genomics Research to Elucidate the Genetics of Rare Diseases: innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Data Coordination and Outreach Center. The Data Coordination and Outreach Center will act as the central point of coordination for the GREGoRi Research Program, and will be responsible for ensuring that the protocols, data, metadata, computational tools and other resources developed as part of GREGoRi are made available to the broader research community.
The GREGoRi Data Coordination and Outreach Center (U01) grant funds the establishment of a central coordination hub for the Genomics Research to Elucidate the Genetics of Rare Diseases: innovation (GREGoRi) initiative. This grant supports organizations seeking to advance rare disease diagnosis through reimagined molecular technologies, analytical approaches, and gene identification methods. The Data Coordination and Outreach Center serves as the backbone of the GREGoRi Research Program, responsible for managing protocols, data, metadata, and computational tools developed across the initiative, making these resources available to the broader research community. Eligible applicants include U.S.-based organizations capable of coordinating multi-institutional research efforts and managing complex genomic datasets. This grant is ideal for research institutions, academic medical centers, and genomics organizations committed to accelerating rare disease diagnosis and improving outcomes for patients with rare genetic disorders. The funding supports infrastructure, personnel, and resources necessary to coordinate data management, ensure interoperability of research tools, and facilitate knowledge dissemination across the rare disease research landscape. Applicants should be prepared to demonstrate expertise in data coordination, genomics research, and community outreach within the rare disease research field.
Funding Facts
● Applications openDeadline
October 30, 2026
Award Amount
Up to $1.3M
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Grant Amount
Up to $1.3M
Deadline
2026-10-30
Grant Type
federal
Application Cycle
Annual deadline (October 30, 2026)
Best For
U.S.-based research institutions, academic medical centers, and genomics organizations focused on rare disease research coordination and data management
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Frequently Asked Questions
Who is eligible for GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)?
U.S.-based organizations and institutions are eligible to apply. Foreign organizations and non-domestic components of U.S. organizations are not eligible. However, foreign components as defined in the NIH Grants Policy Statement are allowed as part of U.S. organization applications. Clinical trials are not permitted under this funding mechanism. For complete eligibility requirements, refer to Section III of the Notice of Funding Opportunity (NOFO) on the official NIH website.
How much funding does GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) provide?
Funding ranges from approximately $1,250,000 per award cycle. The exact amount may vary based on the scope of the proposed project and available appropriations. Contact the NIH program officer or review the current NOFO for the most recent funding information.
How do I apply for GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)?
Applications are submitted through the NIH electronic submission system (Grants.gov or eRA Commons). Applicants should review the Notice of Funding Opportunity (NOFO) for specific submission requirements, forms, and deadlines. The next deadline is October 30, 2026. For detailed application instructions, visit the official NIH GREGoRi initiative website and consult with your organization's grants management office.
What can GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed) funding be used for?
Funding supports the establishment and operation of the GREGoRi Data Coordination and Outreach Center, including: managing genomic data and metadata from GREGoRi research efforts; developing and maintaining computational tools and analytical resources; coordinating protocols and standards across the research network; facilitating data sharing and access for the broader research community; and conducting outreach activities to disseminate findings. Clinical trial activities are not eligible for funding under this mechanism.
Last updated: July 5, 2026