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Grant

In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)

Nationwide

About

This funding opportunity aims to support the development of in vivo high-resolution structural and functional imaging technologies for the living human inner ear. Proposed projects should focus on improving the resolution of current imaging techniques or developing new imaging techniques that can visualize inner ear structures in vivo with significantly greater detail and accuracy than currently possible. Both structural and functional aspects, including visualizing dynamic elements are important to development of new and improved techniques. Projects may also focus on developing new imaging probes or contrast agents that can enhance visualization of the inner ear structures. Ultimately, research supported in response to this RFA is to encourage technologies that allow, for example, structures such as hair cells, otoliths, membranes, ions, and vasculature to be viewed in detail in awake patients in a clinical setting using non-invasive techniques. To achieve this goal, a multi-disciplinary team approach that takes advantage of the expertise of each team member is highly encouraged. Studies in humans and intermediate studies in animals, but not non-mammalian species, may be proposed to develop or advance the needed technology. Any intermediate studies must articulate a clear path of the proposed methodology to application in awake humans or define the limitations and the usefulness in anesthetized humans.

The In Vivo High-Resolution Imaging for Inner Ear Visualization grant supports innovative research and development of advanced imaging technologies designed to visualize the living human inner ear with unprecedented detail and clarity. This funding opportunity is ideal for multidisciplinary research teams including biomedical engineers, otolaryngologists, imaging scientists, and technology developers who are working to improve or create new imaging techniques for inner ear structures. The grant encourages projects that advance both structural and functional imaging capabilities, enabling visualization of critical components such as hair cells, otoliths, membranes, ions, and vasculature in awake patients using non-invasive clinical methods. Applicants may propose human studies, intermediate animal studies in mammals, or combination approaches that demonstrate a clear pathway toward human clinical application. This is particularly valuable for researchers seeking to develop breakthrough technologies that could transform inner ear diagnosis, monitoring, and treatment. The program welcomes applications from diverse institution types, including HBCUs, Hispanic-serving institutions, and other underrepresented groups in research. With funding up to $500,000 available and a deadline of October 1, 2026, this represents a significant opportunity for teams committed to advancing inner ear imaging technology and improving patient outcomes in hearing and balance disorders.

Funding Facts

● Applications open

Deadline

October 1, 2026

Award Amount

Up to $500K

Who can apply

Public and State controlled institutions of higher educationFor profit organizations other than small businessesOthers (see text field entitled "Additional Information o...City or township governmentsIndependent school districtsNative American tribal organizations (other than Federall...+9 more
Apply on Grants.gov

Last verified July 5, 2026 · Source: Grants.gov

Grant Details

Grant Amount

Up to $500K

Deadline

2026-10-01

Grant Type

federal

Application Cycle

Annual cycle with October 1, 2026 deadline

Best For

Multidisciplinary research teams developing advanced imaging technologies for inner ear visualization; institutions serving underrepresented populations in research

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Govern

Frequently Asked Questions

Who is eligible for In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)?

Eligible applicants include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), HBCUs, Hispanic-serving Institutions, Faith-based and Community-based Organizations, Indian/Native American Tribal Governments, and Eligible Federal Agencies. For complete and current eligibility criteria, visit the official NIH or funding agency website.

How much funding does In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional) provide?

Funding ranges from up to $500,000. The specific amount awarded may vary based on project scope, research design, and review outcomes. Check the official funding announcement for detailed budget information and any fiscal year variations.

How do I apply for In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)?

Applications typically follow the NIH R01 grant submission process through Grants.gov. You will need to submit a detailed research proposal, budget narrative, and supporting documentation demonstrating your team's capacity to develop or advance inner ear imaging technologies. Visit the official NIH or relevant funding agency website for specific submission guidelines, required forms, and the application portal.

What can In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional) funding be used for?

Funding supports development and refinement of imaging technologies and techniques for visualizing inner ear structures in vivo. Allowable uses include developing new imaging probes or contrast agents, improving resolution of existing techniques, conducting human and mammalian animal studies, and advancing technologies toward non-invasive clinical application in awake patients. Clinical trial components are optional.

Last updated: July 5, 2026