NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
About
The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorders (SUD) trajectory (e. g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e. g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e. g. anxiety, stress, poor maternal care, social defeat, and other paradigms). Applications may examine any type of genomic variant, including single nucleotide variants (SNVs), indels, large and small structural variants, and all types of mobile DNA. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. Other areas of interest include genomics analysis at the circuit level and the application of neuroscience to genomics studies. NIDA expects these studies to uncover novel mechanisms that contribute to various stages across the SUD trajectory and inform future studies about potential targets and therapeutic strategies for addiction.
The NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed) is a nationwide federal grant opportunity designed for researchers and institutions seeking to advance understanding of the genetic and genomic basis of substance use disorders (SUD) and addiction-related behaviors. This program funds research that identifies genetic, genomic, and molecular variants underlying addictive behaviors, vulnerability to different stages of SUD progression, and associated behavioral phenotypes like impulsivity and novelty seeking. Eligible applicants include HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, AANAPISIs, tribal governments, faith-based and community-based organizations, and federal agencies. Researchers can explore any type of genomic variant, including SNVs, indels, structural variants, and mobile DNA. The program particularly encourages multi-omics approaches, data-based integration of multi-level omics data, gene network delineation, and neuroscience applications to genomics. If your organization conducts animal genomics research aimed at uncovering novel mechanisms across the SUD trajectory and identifying therapeutic targets, this grant supports your mission to advance addiction science and inform future treatment strategies.
Funding Facts
● Applications openDeadline
February 11, 2027
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Funding Range
Varies by cycle
Deadline
2027-02-11
Grant Type
federal
Application Cycle
Annual
Best For
Research institutions, HBCUs, Hispanic-serving institutions, tribal governments, and community-based organizations conducting animal genomics research on substance use disorders
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Govern
Frequently Asked Questions
Who is eligible for NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)?
Eligible applicants include Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), eligible federal agencies, faith-based and community-based organizations, and Indian/Native American tribal governments. For complete and current eligibility requirements, visit the official NIDA grant announcement on grants.nih.gov.
How much funding does NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed) provide?
Specific funding amounts are not specified for this funding cycle. Award amounts typically vary based on the scope and nature of proposed research. Consult the official NIDA grant announcement for current funding details and budget guidelines.
How do I apply for NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)?
Applications are submitted through the NIH grants portal (grants.nih.gov). You will need to prepare a research proposal that clearly describes your animal genomics study, the genetic or genomic variants you plan to examine, and how your work addresses SUD-related phenotypes or behaviors. Ensure your institution has an active DUNS number and is registered in SAM.gov. The application deadline is February 11, 2027. Visit the official NIDA website and grants.nih.gov for detailed application instructions, required forms, and submission guidelines.
What can NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed) funding be used for?
Funding supports research that identifies genetic, genomic, and molecular (epi)genetic variants underlying addictive behaviors, substance use disorder vulnerability and progression, and associated behaviors and comorbidities. This includes studies examining SNVs, indels, large and small structural variants, mobile DNA, multi-omics approaches, gene network analysis, circuit-level genomics analysis, and functional characterization of genetic or epigenetic variants. Research must use animal models and cannot include clinical trials.
Last updated: July 5, 2026