Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
About
NIMH seeks applications for pilot research to adapt, optimize, and test behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. This notice of funding opportunity (NOFO) supports pilot clinical trials designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings. Applications should aim to conduct a preliminary test of the intervention's impact on sleep and mental health outcomes, as well as an examination of the mechanisms that underlie the intervention's effectiveness, and to obtain preliminary data needed as a prerequisite for larger-scale effectiveness trials. In addition, interdisciplinary, collaborative teams of investigators from the fields of mental health, sleep medicine, developmental science, clinical trials research methods, behavioral economics, implementation science, data science, and human computer interaction are encouraged.
The National Institute of Mental Health (NIMH) is seeking applications for pilot research through this R34 Clinical Trial Required grant to support the development and testing of behavioral sleep interventions targeting adolescents and young adults who have or are at risk for mental health disorders. This funding opportunity is designed for research teams seeking to adapt, optimize, and evaluate innovative approaches to addressing sleep problems in this vulnerable population. Researchers can use this grant to conduct preliminary clinical trials that assess the feasibility, tolerability, acceptability, safety, and potential effectiveness of behavioral interventions in real-world settings. The grant supports investigations into how these interventions impact both sleep and mental health outcomes, as well as examinations of the underlying mechanisms of effectiveness. Interdisciplinary teams are particularly encouraged to apply, including researchers from mental health, sleep medicine, developmental science, clinical trials methodology, behavioral economics, implementation science, data science, and human-computer interaction. This is an excellent opportunity for research institutions and organizations committed to improving mental health outcomes through evidence-based sleep interventions. Applicants should be prepared to gather preliminary data that will support larger-scale effectiveness trials and demonstrate the clinical significance of their approach.
Funding Facts
● Applications openDeadline
October 22, 2026
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Funding Range
Varies by cycle - see official NOFO
Deadline
2026-10-22
Grant Type
federal
Application Cycle
Annual - Deadline October 22, 2026
Best For
Research institutions, academic medical centers, and interdisciplinary research teams focused on adolescent and young adult mental health and sleep medicine
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Frequently Asked Questions
Who is eligible for Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)?
Domestic U.S. Organizations are eligible to apply. Non-domestic (non-U.S.) entities and foreign organizations are not eligible. Non-domestic components of U.S. organizations and foreign components as defined in the NIH Grants Policy Statement are not allowed. For detailed eligibility requirements, refer to Section III of the official Notice of Funding Opportunity (NOFO) on the NIH website.
How much funding does Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required) provide?
The specific funding amount is not specified in the current listing. Visit the official NIH NIMH website or the detailed NOFO for information about the funding range and budget limitations for this grant cycle.
How do I apply for Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)?
Applications must be submitted through the official NIH application portal. The deadline for this funding opportunity is October 22, 2026. Applicants should review the complete Notice of Funding Opportunity (NOFO) on the NIH website for detailed instructions, required forms, and submission guidelines. Contact the NIMH program officer for technical assistance with your application.
What can Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required) funding be used for?
Funding supports pilot clinical trials designed to adapt, optimize, and test behavioral interventions for sleep problems in adolescents and young adults with or at risk for mental health disorders. Allowable uses include evaluating feasibility, tolerability, acceptability, safety, and potential effectiveness of interventions in real-world settings; examining mechanisms underlying intervention effectiveness; conducting preliminary tests of intervention impact on sleep and mental health outcomes; and gathering preliminary data to support larger-scale effectiveness trials.
Last updated: July 5, 2026