Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)
About
This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.
The Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs) program, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), supports collaborative research infrastructure for institutions conducting digestive and liver diseases research. This Centers program is designed for research institutions that want to enhance communication, collaboration, and research effectiveness by bringing together basic and clinical investigators. The program funds shared resources and core facilities that foster productivity, synergy, and innovation among research teams working on digestive or liver disease-related projects. Institutions with a strong, established research base in digestive and/or liver diseases are eligible to apply. The funding supports the development of centralized research cores that enable cost-effective resource sharing across multiple investigators and projects. Research institutions interested in strengthening their digestive diseases research programs through collaborative infrastructure should consider applying. The program emphasizes integrated, theme-based research approaches that align with NIDDK's mission. Applicants must demonstrate sufficient ongoing research support and a clear central theme that unifies their Center's research focus.
Funding Facts
● Applications openDeadline
February 10, 2027
Award Amount
Up to $750K
Who can apply
Last verified July 5, 2026 · Source: Grants.gov
Grant Details
Grant Amount
Up to $750K
Deadline
2027-02-10
Grant Type
federal
Application Cycle
Annual
Best For
Research institutions with established digestive and liver diseases research programs seeking to develop collaborative research infrastructure
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Only institutions at which there is a strong ongoing base of digestive and/or liver diseases-relevant research that relates to the proposed theme of the Center are eligible. The already funded research base must have at least $3 million per year in direct costs of supported research within a propose
Frequently Asked Questions
Who is eligible for Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)?
Only institutions with a strong ongoing research base in digestive and/or liver diseases are eligible. Eligible institutions must have at least $3 million per year in direct costs of supported research that relates to the proposed Center theme. The research focus must align with NIDDK's primary mission and not fall under the primary funding responsibility of other NIH Institutes or Centers. For complete eligibility details, refer to Section III of the official Notice of Funding Opportunity (NOFO).
How much funding does Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional) provide?
Funding ranges from not specified to $750,000. The actual award amount may vary depending on the scope of the proposed Center, the number and complexity of shared core resources, and the strength of the research base. Contact NIDDK or consult the official NOFO for information about funding levels for current funding cycles.
How do I apply for Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)?
Applications are submitted through the NIH grants submission system. Interested institutions should review the complete Notice of Funding Opportunity (NOFO) for specific application requirements, formatting guidelines, and required components. The application must include a clear central research theme, description of shared research cores, and evidence of institutional research infrastructure. Visit the official NIDDK website or grants.nih.gov for the complete NOFO, application instructions, and submission deadlines.
What can Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional) funding be used for?
Funding supports shared research resources and core facilities that enhance collaboration among digestive and liver diseases researchers. This includes infrastructure for core facilities such as analytical services, specialized equipment, data management systems, and other shared resources that advance research productivity. The program emphasizes cost-effective resource sharing that benefits multiple investigators and research projects within the Center's theme. Funding is not intended for direct research project costs but rather for the administrative and operational infrastructure that supports research collaboration.
Last updated: July 5, 2026