About Starting a Business in Memphis
Memphis, Tennessee offers a compelling opportunity for entrepreneurs seeking to launch a business in a major metropolitan area with a rich industrial heritage and growing innovation ecosystem. Home to over 651,000 residents, Memphis has evolved from its roots as a cotton trading hub into a diversified economy anchored by logistics, healthcare, music and entertainment, and professional services. The city's strategic location on the Mississippi River and position as a major FedEx distribution center make it a natural choice for supply chain and e-commerce businesses.
The cost of living remains significantly lower than comparable major cities like Nashville or Atlanta, allowing entrepreneurs to stretch startup capital further while accessing a large regional market. Downtown Memphis and the Cooper-Young neighborhood have emerged as creative hubs attracting startups and freelancers, while the South Memphis area continues revitalization efforts creating opportunities for entrepreneurs. Entrepreneurs should explore state-level support networks and chamber of commerce resources to supplement their business planning efforts.
SBA Resources
1 in Memphis
Nationwide Resources
These resources are available anywhere in the US
Ben & Jerry's Foundation Grassroots Organizing Grants
Nationwide
Black Founders Matter Grant
Nationwide
Comcast RISE Grant Program
Nationwide
EDA Economic Development Grants
Nationwide
FedEx Small Business Grant Contest
Nationwide
Founder Institute
Nationwide
Google.org Impact Challenge
Nationwide
HelloAlice Small Business Grants
Nationwide
Tips for Entrepreneurs in Memphis
- 1Leverage Memphis's logistics advantage—if your business involves product distribution or supply chain services, the city's FedEx hub and river location provide unmatched infrastructure and networking opportunities with established players in the industry.
- 2Explore the Cooper-Young and Overton Square neighborhoods as affordable locations for creative businesses, retail, or service-based startups; these areas offer character, walkability, and emerging entrepreneurial communities.
- 3Connect with the Greater Memphis Chamber of Commerce early—since SparkLocal shows limited coworking and accelerator resources, the chamber becomes your primary networking hub for business connections, local knowledge, and growth opportunities.
- 4Consider the healthcare and medical technology sectors given Memphis's major medical institutions and research centers; these industries offer stable growth and partnership opportunities for specialized service providers.
- 5Take advantage of Tennessee's favorable tax climate and lower operating costs compared to neighboring states; reinvest savings into marketing and talent acquisition to compete regionally while building your business foundation.
Starting a Business in Memphis — FAQ
What do I need to start a business in Memphis, TN?
To start a business in Memphis, you'll need to register your business with the Tennessee Secretary of State and obtain an Employer Identification Number (EIN) from the IRS. Depending on your industry, you may need specific licenses from the City of Memphis and Shelby County—such as health permits for food service, professional licenses for healthcare, or specific permits for construction or retail. Register for Tennessee sales tax if you'll be selling taxable goods, and ensure you comply with local zoning requirements for your business location.
What industries are growing in Memphis?
Memphis's economy is driven by logistics and distribution, with FedEx's global operations headquartered in the area, creating opportunities for supply chain and transportation startups. Healthcare is another major sector, with major medical centers and research institutions offering opportunities in medical technology and healthcare services. The music and entertainment industry remains significant, particularly around Beale Street and the historic Sun Studio area, attracting creative entrepreneurs. Additionally, professional services, advanced manufacturing, and food and beverage businesses are growing sectors in the region.
Are there grants for small businesses in Memphis?
SparkLocal currently lists 0 grants available in our Memphis directory. However, entrepreneurs should explore the Tennessee Small Business Development Center (SBDC), which offers free counseling and may provide information about state-level grant opportunities. The City of Memphis and Shelby County also occasionally offer economic development incentives for businesses in targeted areas. Additionally, review SBA-backed loan programs and microfinance options through nonprofit lenders, and check with the Greater Memphis Chamber of Commerce for any current funding initiatives.
Where can I find coworking space in Memphis?
SparkLocal currently lists 0 coworking spaces in our Memphis directory, but the city has been developing flexible workspace options. The Cooper-Young neighborhood and downtown Memphis areas are popular for entrepreneurs seeking shared office environments and creative spaces. Consider reaching out directly to the Greater Memphis Chamber of Commerce, local real estate agencies, and visiting neighborhoods like Overton Square and the South Main Arts District, where independent landlords and property developers often offer flexible lease terms. Many entrepreneurs also work remotely or rent traditional office suites in business parks throughout the city.
What free business help is available in Memphis?
SparkLocal currently lists 0 SBA resources in our Memphis directory. For free business assistance, contact the Tennessee Small Business Development Center (SBDC) at a nearby location, which provides counseling on business planning, marketing, and finances. SCORE Memphis offers free mentoring from experienced business professionals, and the Greater Memphis Chamber of Commerce provides networking, resources, and advocacy for local businesses. The City of Memphis Economic Development Office can also direct you to training programs and business support services available through municipal and county programs.
Is Memphis a good place to start a business?
Memphis offers distinct advantages for entrepreneurs: lower costs of living and real estate compared to other major cities, a strategic location for distribution and logistics, a large regional customer base, and a diverse economy spanning healthcare, music, professional services, and manufacturing. The city's ongoing revitalization efforts are attracting investment and talent, particularly in downtown and emerging neighborhoods. However, like any city, Memphis has challenges including competitive business environments in established sectors and a developing startup infrastructure. For businesses in logistics, healthcare, creative industries, or services, Memphis presents solid fundamentals and growth potential.
Starting a business in Memphis?
SparkLocal creates a personalized launch plan with the exact resources you need based on your business idea, budget, and goals.
Create Your Launch PlanLast updated: March 1, 2026
Stay Updated
Get notified when new resources are added in Memphis, TN.